S-PLEX Human Tau (pT181) Kit, SECTOR (5 PL)

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S-PLEX Human Tau (pT181) Kit, SECTOR (5 PL)

品牌： MSD

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S-PLEX is MSD’s ultrasensitive assay platform. It can dramatically improve the sensitivity of immunoassays, reducing the lower limit of detection (LLOD) by 10- to 1000-fold over other assay methods. The S-PLEX Human Tau (pT181) Assay has the essential components for an ultrasensitive assay that measures phosphorylated Tau (T181) in a single-analyte format. For detailed instructions on running the Tau (pT181) assay, please see the product insert in the "Documentation" tab below.

Related Key Terms:
Neurobiology/Neurodegeneration, Phosphorylated Tau, Threonine181, MAPT, DDPAC, MTBT2, PPND, PPP1R103

Specifications
Kit Contents
Documentation
References

Kit Contents for Catalog No. K151AGMS-1

Product Description	Storage	Quantity per Kit
Diluent 2	≤-10 °C	1 each (8 mL)

S-PLEX Human Tau (pT181) Antibody Set	2-8 °C	1 each (1 plate size)

S-PLEX Coating Reagent C1	≤-70 °C	1 vial (300 μL)

S-PLEX Detect D2	≤-70 °C	1 each (50 μL)

S-PLEX Detect D1	≤-70 °C	1 each (1.7 mL)

S-PLEX 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)

Diluent 100	2-8 °C	1 bottle (50 mL)

Diluent 59	2-8 °C	1 bottle (8 mL)

MSD GOLD Read Buffer B	RT	1 bottle (18 mL)

S-PLEX Enhance E1	≤-10 °C	1 each (1.7 mL)

S-PLEX Enhance E2	≤-10 °C	1 vial (1.7 mL)

S-PLEX Enhance E3	≤-70 °C	1 each (50 μL)

Blocker S1	≤-10 °C	1 vial (500 μL)

Kit Contents for Catalog No. K151AGMS-2

Product Description	Storage	Quantity per Kit
Diluent 2	≤-10 °C	1 each (40 mL)

S-PLEX Human Tau (pT181) Antibody Set	2-8 °C	1 each (5 plate size)

S-PLEX Coating Reagent C1	≤-70 °C	1 vial (300 μL)

S-PLEX Detect D2	≤-70 °C	5 each (50 μL)

S-PLEX Detect D1	≤-70 °C	5 each (1.7 mL)

S-PLEX 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)

Diluent 100	2-8 °C	1 bottle (50 mL)

Diluent 59	2-8 °C	1 bottle (40 mL)

MSD GOLD Read Buffer B	RT	1 bottle (90 mL)

S-PLEX Enhance E1	≤-10 °C	5 each (1.7 mL)

S-PLEX Enhance E2	≤-10 °C	5 vial (1.7 mL)

S-PLEX Enhance E3	≤-70 °C	5 each (50 μL)

Blocker S1	≤-10 °C	1 vial (500 μL)

Kit Contents for Catalog No. K151AGMS-4

Product Description	Storage	Quantity per Kit
Diluent 2	≤-10 °C	5 each (40 mL)

S-PLEX Human Tau (pT181) Antibody Set	2-8 °C	5 each (5 plate size)

S-PLEX Coating Reagent C1	≤-70 °C	5 vial (300 μL)

S-PLEX Detect D2	≤-70 °C	25 each (50 μL)

S-PLEX Detect D1	≤-70 °C	25 each (1.7 mL)

S-PLEX 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)

Diluent 100	2-8 °C	5 bottle (50 mL)

Diluent 59	2-8 °C	5 bottle (40 mL)

MSD GOLD Read Buffer B	RT	5 bottle (90 mL)

S-PLEX Enhance E1	≤-10 °C	25 each (1.7 mL)

S-PLEX Enhance E2	≤-10 °C	25 vial (1.7 mL)

S-PLEX Enhance E3	≤-70 °C	25 each (50 μL)

Blocker S1	≤-10 °C	5 vial (500 μL)

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货号：

K151AGMS-2

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询价大包装询价

Application(s)		Neurobiology/Neurodegeneration, Alzheimer’s Disease
Analyte(s)		Tau (pT181)
Species		Human
Instrument(s)		SECTOR Imager 2400 , MESO QuickPlex SQ 120MM, MESO SECTOR S 600 , SECTOR Imager 6000 , MESO SECTOR S 600MM, MESO QuickPlex SQ 120
Plate Type		96-well
Capture Antibody		Mouse monoclonal
Detection Antibody		Mouse monoclonal
LLOD (Sensitivity)		77 fg/mL
Dynamic Range		77 - 990,000 fg/mL
Sample Type		Serum, Plasma, CSF, Cell Culture Supernatant, Urine
Recombinant standards		Expressed in Human cell line
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Condition		Multi-Component
Gene ID(s)		4137
UniProt ID(s)		P10636
Schedule B Code		3822.19.0000

Product Inserts		S-PLEX Tau pT181 Kit Product Insert
Certificate of analysis		K00S0201 K00S0168 K00S0068 K00S0056 K00S0109
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 2, Diluent 3, Diluent 5, Diluent 7 and Diluent 8 Diluent 50, Diluent 56, Diluent 61, Diluent 100, and Diluent 101 Diluent 57, Diluent 58, and Diluent 59 MSD GOLD Read Buffer B
Scientific Posters		Validation of Novel Ultrasensitive Assays for Detection of Phosphorylated Tau (pT181 and pT217) in Human Plasma, Serum, and Cerebrospinal Fluid

Title	Journal	Year
Plasma biomarkers for diagnosis of Alzheimer’s disease and prediction of cognitive decline in individuals with mild cognitive impairment Pia Kivisäkk, Thadryan Sweeney, Becky C. Carlyle, Bianca A. Trombetta, Kathryn LaCasse, Leena El-Mufti, Idil Tuncali, Lori B. Chibnik, Sudeshna Das, Clemens R. Scherzer, Keith A. Johnson, Bradford C. Dickerson, Teresa Gomez-Isla, Deborah Blacker, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Anahit Aghvanyan, Pradeepthi Bathala, Christopher Campbell, George Sigal, Martin Stengelin, Steven E. Arnold	Frontiers in Neurology	2023