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Sandoz 58-035

产品介绍
产品介绍
产品信息
商品描述
Sandoz 58-035 is an inhibitor of Acyl-CoA cholesterol acyltransferase (SOAT/ACAT). Sandoz 58-035 inhibits the accumulation of cholesteryl esters and inhibits the esterification of cholesterol by 95% in arterial smooth muscle cells in culture. It does not affect the triglyceride metabolism by the gut.

分子量
465.79

纯度
≥98%

可溶性
Soluble in DMSO (16 mg/ml). Insoluble in water.

外观
white powder

IC50
Acyl coenzyme A:cholesterol acyltransferase 1: IC50 = 0.3 µM (rat)

应用
实验应用
An inhibitor of Acyl-CoA cholesterol acyltransferase (SOAT/ACAT)

背景
别名
3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenethyl]propanamide; SA 58-035

分子式
C30H47NOSi

CAS号
78934-83-5

沸点
584.37° C at 760 mmHg (Predicted)

MDL
MFCD00161339

密度
0.95 g/cm3 (Predicted)

折射率
n20D 1.51 (Predicted)

制备和贮存
保存方式
Store at 4° C
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