SASH1 (X1)

鼠

抗-SASH1 抗体 X1 是小鼠单克隆 IgG1 (kappa轻链)，SASH1抗体，规格为100 µg/ml raised against amino acids 1066-1175 representing partial length SASH1 of human origin 推荐用于 human 来源的SASH1 WB, IP 和 ELISA检测 目前，我们还没有完成SASH1 抗体 (X1)的首选二抗检测试剂的鉴定。这项工作正在进行中。 SASH1 Antibody (X1) is a high quality monoclonal SASH1 antibody (also designated SASH1 antibody) suitable for the detection of the SASH1 protein of human origin. SASH1 Antibody (X1) is available as the non-conjugated anti-SASH1 antibody. SASH1 (SAM and SH3 domain-containing protein 1), also known as PEPE1 (Proline-glutamate repeat-containing protein), is a 1247 amino acid protein that is significantly downregulated in the majority of primary breast tumor tissues, breast cancer cell lines, lung and thyroid tumors, as well as in certain colon carcinomas. It has been hypothesized that its expression is suppressed not due to mutation of the SASH1 gene, but instead via other mechanisms, such as promoter methylation. As a member of the SH3-domain containing expressed in lymphocytes (SLY1) gene family, SASH1 contains two sterile alpha modules (SAMs) and one Src homology-3 (SH3) domain, motifs that are predominantly found in adaptors, scaffold proteins and signaling molecules. Downregulation of SASH1 expression correlates with the formation of distant metastasis and is considered a negative prognostic parameter for patient survival.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-169253.

脯氨酸-谷氨酸重复序列的蛋白质抗体、磷酸盐缓冲液

HumanSASH1

human

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