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SBI-115
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产品介绍
产品介绍
产品信息
商品描述
SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.
分子量
340.78
纯度
98%
可溶性
DMSO : 100 mg/mL (293.44 mM)
外观
White to off-white Solid
In vitro(体外研究)
SBI-115 (100-200 µM, 24 hours) inhibits proliferation triggered by pre-treatment of cystic cholangiocytes with Taurolithocholic acid (TLCA) in shRNA-transfected ADPKD cholangiocytes.Cell Proliferation AssayCell Line:shRNA-transfected ADPKD cholangiocytesConcentration:100, 200 µMIncubation Time:24 hoursResult:Inhibited proliferation (by 32-48%) triggered by pre-treatment of cystic cholangiocytes with TLCA.
背景
分子式
C14H13ClN2O4S
CAS号
882366-16-7
制备和贮存
保存方式
Store at -20℃ for three years（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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