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产品介绍
产品信息
商品描述
SC 58125 is a selective, time-dependent, and irreversible cyclooxygenase-2 (Cox-2) inhibitor that displays anti-inflammatory properties. In addition to inhibiting Cox-2 (IC50 of 0.04 μM), SC 58125 is found to reversibly inhibit Cox-1 (IC50 of >100 μM), which is expressed in most tissues and organs. Experiments suggest that SC 58125 is also capable of suppressing cell proliferation by causing a progression delay at the G2/M transition.
分子量
384.35
纯度
98%
可溶性
Soluble in water (700 mg/L at 25 °C), chloroform (44.51 g/100mL at 25 °C), dichloromethane (19.20 g/100mL at 25 °C), methanol (9.98 g/100mL at 25 °C), DMSO (50 mM), ethanol (1.28 g/100mL at 25 °C)
应用
实验应用
A selective Cox-2 inhibitor
背景
分子式
C17H12F4N2O2S
CAS号
162054-19-5
制备和贮存
保存方式
Store at 4° C
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