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SCH 79797二盐酸盐

SCH 79797二盐酸盐

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品牌: Absin
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分子式:
C23H25N5•2HCl
分子量:
444.40
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产品介绍
产品介绍
产品信息
商品描述

SCH 79797 dihydrochloride is a nonpeptide selective inhibitor of Thrombin R (PAR1), a thrombin-activated receptor. PARs have been described as G protein-coupled receptors that regulate endothelial nitric oxide synthase activity via phosphorylation of the enzyme at various sites. SCH 79797 dihydrochloride has also been reported to contain a high affinity for thrombin receptor-activating peptides, such as α-thrombin.

分子量
444.40
纯度

≥99%

可溶性
Soluble in ethanol (25 mM), and DMSO (50 mM).
IC50
PAR1 receptor: IC50 = 70 nM
应用
实验应用
A strong, selective non-peptide Thrombin R inhibitor
背景
分子式
C23H25N5•2HCl
CAS号
245520-69-8
沸点
678.3° C at 760 mmHg (Predicted)
MDL
MFCD04039788
制备和贮存
保存方式
Desiccate at room temperature
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货号:
abs42027132-10mg
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