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产品介绍
产品信息
商品描述
SCH 79797 dihydrochloride is a nonpeptide selective inhibitor of Thrombin R (PAR1), a thrombin-activated receptor. PARs have been described as G protein-coupled receptors that regulate endothelial nitric oxide synthase activity via phosphorylation of the enzyme at various sites. SCH 79797 dihydrochloride has also been reported to contain a high affinity for thrombin receptor-activating peptides, such as α-thrombin.

分子量
444.40

纯度
≥99%

可溶性
Soluble in ethanol (25 mM), and DMSO (50 mM).

IC50
PAR1 receptor: IC50 = 70 nM

应用
实验应用
A strong, selective non-peptide Thrombin R inhibitor

背景
分子式
C23H25N5•2HCl

CAS号
245520-69-8

沸点
678.3° C at 760 mmHg (Predicted)

MDL
MFCD04039788

制备和贮存
保存方式
Desiccate at room temperature
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