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SDHB
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产品介绍
产品介绍
产品信息
免疫原
Purified recombinant protein fragment corresponding to aa29-280 from human SDHB, expressed in E. coli.
产品用途
Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested.
简单描述
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
同种型
IgG1
克隆号
2E8B11
克隆类别
Monoclonal
纯度
Purified
应用
实验应用
Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested.
推荐用量
ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Optimal dilutions to be determined by the researcher.
反应种属
Mouse
交叉反应性
Hu
目标/特异性
Recognizes human SDHB.
背景
别名
IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
制备和贮存
保存方式
-20°C
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