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产品介绍
产品信息
商品描述
Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.
分子量
482.44
纯度
98%
可溶性
易溶于丙酮、乙酸乙酯、甲醇、乙醇，略溶于氯仿，几乎不溶于水。
外观
类白色结晶性粉末
应用
实验应用
A major active constituent of silymarin which inhibits mitogen-activated protein kinase (MAPK)
背景
别名
西利马林
分子式
C25H22O10
CAS号
22888-70-6
制备和贮存
保存方式
-20° C，有效期2年。
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