SKF 86466 hydrochloride (10 mg)

10220250

Potent and selective α₂ antagonist

232.15

6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride

Potent and selective α₂ antagonist at pre- and post-junctional α₂-adrenoceptors (K_i values are 13 and 17 nM respectively). Exhibits antihypertensive activity in a rat model.

≥98% (HPLC)

Soluble to 100 mM in water and to 100 mM in DMSO

CN2CCC1=CC=CC(Cl)=C1CC2.Cl

C₁₁H₁₄ClN.HCl

86129-54-6