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SQSTM1/p62 Recombinant Rabbit mAb (S-R346)

SQSTM1/p62 Recombinant Rabbit mAb (S-R346)

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品牌: STARTER
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反应种属:
Hu、Ms、Rt
来源宿主:
Rabbit
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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
纯化方式
Protein A
宿主
Rabbit
同种型
IgG
克隆号
S-R346
浓度
0.5 mg/ml
性状
Liquid
缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
产品类型
Recombinant mAb
应用
实验应用
WB、IHC-P、ICC、ICFCM
反应种属
Hu、Ms、Rt
稀释度
  • WB

    1:1000
  • IHC-P

    1:2000
  • ICC

    1:500
  • ICFCM

    1:500
背景
别名
Sequestosome-1, EBI3-associated protein of 60 kDa (EBIAP, p60), Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, ORCA, OSIL
背景

Sequestosome-1 is a protein that in humans is encoded by the SQSTM1 gene. Also known as the ubiquitin-binding protein p62, it is an autophagosome cargo protein that targets other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence and senescence-associated secretory phenotype. Mutations in SQSTM1 are a common cause of Paget's disease of bone.

细胞定位
Cytoplasm
制备和贮存
保存方式

12 months from date of receipt / reconstitution, -20 °C as supplied

数据库链接
Accession
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货号:
S0B0000-1ml
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询价
1ml
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