SR-1F (5-hydroxytryptamine Receptor 1F, 5-HT-1F, 5-HT1F, Serotonin Receptor 1F, HTR1F, HTR1EL)

Synthetic peptide corresponding to amino acids 100-150 of Human SR-1F.

Suitable for use in Immunofluorescence, Western Blot. Other applications not tested.

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

IgG

Polyclonal

Purified by immunoaffinity chromatography.

Suitable for use in Immunofluorescence, Western Blot. Other applications not tested.

Western Blot: 1:500-1:1000 Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher.

Rabbit

Hu Mo Rt

Recognizes endogenous levels of SR-1F. Species Crossreactivity: Human, mouse, rat

5-hydroxytryptamine Receptor 1F, 5-HT-1F, 5-HT1F, Serotonin Receptor 1F, HTR1F, HTR1EL

P30939