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SR-318
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产品介绍
产品介绍
产品信息
抗原名称
TNF-α:283 nM, p38α:5 nM, p38α/β:6.11 μM, p38β:32 nM
商品描述
SR-318 potently inhibits the TNF-α release in whole blood (IC50 = 283 nM). SR-318 is a potent and highly selective inhibitor of p38 MAPK. The IC50 values are 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively.
分子量
459.58
纯度
98%
可溶性
DMSO:125 mg/mL (271.99 mM)
In vitro(体外研究)
SR-318 presents a potent and selective type-II p38α/β inhibitor,It is used as a chemical probe for targeting this particular inactive state of these two p38 isoforms.
背景
分子式
C27H33N5O2
CAS号
2413286-32-3
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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