Stat1 (H-1)

mouse

Stat1抗体(H-1)是小鼠单克隆IgG2a (kappa轻链)，规格为200 µg/ml 特异性抗原位于mouse物种的Stat1α p91的C-terminus的氨基酸718-749之间 推荐用于 mouse, rat 和 human 来源的Stat1 WB, IP, IF 和 ELISA检测 可用于ChIP的TransCruz试剂(sc-398524 X, 200 µg/0.1 ml) 看 Stat1 (C-136): sc-464，可查看有标记的 Stat1 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790 m-IgG Fc BP-HRP and m-IgG2a BP-HRP 是 Stat1 Antibody (H-1) for WB首选应用二抗。这些试剂现在以套装形式提供Stat1 Antibody (H-1) (见下方订购信息). Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and Myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-345, sc-591.

IGG-免疫球蛋白G型抗体

HumanSTAT1

m, r, h

6772;20846