

产品介绍
产品介绍
产品信息
宿主
鼠

简单描述
Stat1抗体(C-111)是小鼠单克隆IgG1 κ, 在125篇文献中引用,规格为200 µg/mlepitope mapping between amino acids 613-739 of Stat1 of human origin抗-Stat1 抗体 (C-111) 推荐用于 WB, IP 和 IF,检测mouse, rat 和human 来源的 Stat1抗-Stat1 抗体 (C-111) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统可用于凝胶迁移和ChIP的TransCruz试剂(sc-417 X, 200 µg/0.1 ml)关于如何获取Stat1 (C-111): sc-417的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 Stat1 Antibody (C-111) for WB 的首选应用二抗。这些试剂现在以套装形式提供Stat1 Antibody (C-111)。 (见下方订购信息).
查看产品引用文献(123) Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and Myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

克隆类别
Replacement monoclonal antibody for: sc-345, sc-591.

组成成分
信号传导转录激活因子1抗体,磷酸盐缓冲液
