p-Stat1 (12C5)

mouse

p-Stat1 抗体 12C5 是小鼠单克隆 IgG1, 在3篇文献中引用，提供 50 µg/0.5 mlraised against a synthetic phosphopeptide corresponding to amino acids Ser 727 of Stat1 of human origin推荐用于 human 来源的Ser 727 phosphorylated Stat1 WB 和 IP检测目前，我们还没有完成p-Stat1 抗体 (12C5)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(3) Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanSTAT1

6772