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p-Stat3 (pS727.49)

产品介绍
产品信息
宿主
鼠

简单描述
p-Stat3抗体(pS727.49)是小鼠单克隆IgG1 κ, 在7篇文献中引用,规格为200 µg/mlraised against a short amino acid sequence containing phosphorylated Ser 727 of Stat3 of human origin推荐用于 mouse, rat 和 human 来源的Ser 727 phosphorylated Stat3 isoform α WB, IP 和 IF检测关于如何获取p-Stat3 (pS727.49): sc-136193的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP 和 m-IgGκ BP-HRP 是 p-Stat3 Antibody (pS727.49) for WB 的首选应用二抗。这些试剂现在以套装形式提供p-Stat3 Antibody (pS727.49)。 (见下方订购信息).
查看产品引用文献(7) Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

组成成分
生长激素抗体、磷酸盐缓冲液

基因

数据库链接
Entrez-Gene ID
6774;20848

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