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TAB2, CT (TGF-beta-activated Kinase 1 and MAP3K7-binding Protein 2, Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 2, TAK1-bindi
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by immunoaffinity chromatography.
抗原名称
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
免疫原
Human TAB2
商品描述
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappa B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
形式
Supplied as a liquid in PBS, 0.02% sodium azide.
产品类型
Polyclonal
应用
实验应用
Immunohistochemistry (IHC)
反应种属
Human
背景
别名
Anti -TAB2, CT (TGF-beta-activated Kinase 1 and MAP3K7-binding Protein 2, Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 2, TAK1-binding Protein 2, TAB-2, TGF-beta-activated Kinase 1-binding Protein 2, KIAA0733, MAP3K7IP2)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
23118
UniProt ID
Q9NYJ8
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