TAF II p105 (TAFAD26A)

mouse

抗-TAF II p105 抗体 TAFAD26A 是小鼠单克隆 IgG1，TAF II p105抗体，规格为100 µg/ml raised against a recombinant protein corresponding to a region near the C-terminus of TAF II p105 of human origin 推荐用于 human 来源的TAF II p105 WB 和 IP检测 关于如何获取TAF II p105 (TAFAD26A): sc-81122的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。 目前，我们还没有完成TAF II p105 抗体 (TAFAD26A)的首选二抗检测试剂的鉴定。这项工作正在进行中。 TAF II p105 Antibody (TAFAD26A) is a high quality monoclonal TAF II p105 antibody (also designated TAF II p105 antibody) suitable for the detection of the TAF II p105 protein of human origin. TAF II p105 Antibody (TAFAD26A) is available as the non-conjugated anti-TAF II p105 antibody. TFIID is a general transcription factor that facilitates the preinitiation complex assembly through direct interactions with the TATA promoter element. TFIID is a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs). TAF II p105, also called TAF4B, is a cell-type specific transcriptional coactivator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamer-dependent transcription. Additionally, TAF II p105 plays an important role in coactivating the transcription factor NF-kappaB and is essential for activation of anti-apoptotic genes such as TNFAIP3. Through its C-terminal histone-fold domain, TAF II p105 can form a heterodimer with TAF12/TAF II p20 that can then form a transcriptional activating octamer with several other TAFs. This protein is localized to the nucleus with cytoplasmic export mediated by a CRM1-independent export pathway. There are two isoforms expressed by alternative splicing.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-85178.

IGG-免疫球蛋白G型抗体

HumanTAF4B

6875