TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subuni

Affinity Purified Purified by Protein A affinity chromatography.

transcription elongation factor B polypeptide 1 isoform b

TCEB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the C-terminal region of human TCEB1

This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Polyclonal

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Human

Anti -TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15)

6921

Q15369 [Other Products]