TCS 2002 (10 mg)

24855958

Potent GSK-3β inhibitor

338.38

2-Methyl-5-[3-[4-(methylsulfinyl)phenyl]-5-benzofuranyl]-1,3,4-oxadiazole

Potent inhibitor of GSK-3β (IC₅₀ = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in the mouse brain.

≥99% (HPLC)

Soluble to 100 mM in DMSO and to 25 mM in ethanol

O=S(C)C(C=C3)=CC=C3C2=COC1=CC=C(C4=NN=C(C)O4)C=C12

C₁₈H₁₄N₂O₃S

1005201-24-0