TCS JNK 5a (10 mg)

766949

Selective inhibitor of JNK2 and JNK3

332.42

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

Selective inhibitor of JNK2 and JNK3 (pIC₅₀ values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38α respectively). Displays no significant activity at a range of other protein kinases including EGFR, ErbB2, cdk2, PLK-1 and Src (pIC₅₀ < 5.0).

≥99% (HPLC)

Soluble to 100 mM in DMSO

O=C(C3=CC=CC4=C3C=CC=C4)NC2=C(C#N)C1=C(S2)CCCC1

C₂₀H₁₆N₂OS

312917-14-9