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HRF (20)

产品介绍
产品介绍
产品信息
宿主
鼠

简单描述
HRF 抗体 20 是小鼠单克隆 IgG1,提供 50 µg/0.5 ml
免疫human物种的HRF的氨基酸91-107
推荐用于 mouse, rat 和 human 来源的HRF WB, IF 和 ELISA检测; not recommended for IP
目前,我们还没有完成HRF 抗体 (20)的首选二抗检测试剂的鉴定。这项工作正在进行中。 Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
单抗

组成成分
IGG-免疫球蛋白G型抗体
