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产品介绍
产品介绍
产品信息
商品描述
Telomerase Inhibitor IX, also called MST-312, is a synthetic compound that acts as a reversible TERT (telomerase) inhibitor, and is described to be more potent than epigallocatechin gallate . UP37 cell studies suggest that in the presence of Telomerase Inhibitor IX, cell growth slows and the cells remain in the G0-G1 cell cycle arrest. In addition, reports indicate that Telomerase Inhibitor IX does not inhibit Taq DNA polymerase .
分子量
380.36
纯度
≥95%
可溶性
Soluble in DMSO (≥20 mg/ml).
IC50
telomerase activity: IC50 = 670 nM (TRAP lysate prepared from U937 cells); Taq DNA polymerase: IC50 = >3 µM
应用
实验应用
A potent, reversible inhibitor of telomerase activity
背景
分子式
C20H16N2O6
CAS号
368449-04-1
沸点
~526.7° C at 760 mmHg (Predicted)
密度
~1.6 g/cm3 (Predicted)
折射率
n20D 1.8 (Predicted)
制备和贮存
保存方式
Store at -20° C
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