

产品介绍
产品介绍
产品信息
纯化方式
>95% (HPLC)

抗原名称
Kir1.1, Kir3.2 K+ channels

商品描述
Tertiapin-Q-ATTO Fluor-488 (#STT-170-AG) is a highly pure, synthetic, and biologically active conjugated peptide toxin.

分子量
3195.5 Da

生物活性
Tertiapin-Q blocks a range of inward rectifier K+ channels (Kir), in particular ROMK1 and GIRK, but with no effect on Kir2 family members1,2. In addition, it was shown to inhibit acetylcholine induced K+ currents in the heart3,4.

可溶性
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min). Avoid exposure to light. The product is lyophilized in 0.5 ml conical vial.

浓度
50-200 nM.

形式
Lyophilized

背景
翻译后修饰
Disulfide bonds between Cys3-Cys14, Cys5-Cys18. Lys21 - C-terminal amidation.

制备和贮存
存储溶液
Up to two weeks at 4°C or three months at -20°C. Avoid exposure to light.

保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. Avoid exposure to light.
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