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产品介绍
产品介绍
产品信息
克隆号
OKT-9

克隆类别
单抗

Product Details
The OKT-9 monoclonal antibody reacts with human CD71 also known as Transferrin receptor protein 1 (TfR1). CD71 is a 95 kDa type II transmembrane glycoprotein that is expressed by immature proliferating cells, reticulocytes, and erythroid precursors. CD71 influences cellular proliferation by mediating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis. CD71 is a potential new target in cases of human leukemia and lymphoma.Specifications
Isotype | Mouse IgG1, κ |
---|---|
Recommended Isotype Control(s) | InVivoMAb mouse IgG1 isotype control, unknown specificity |
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Immunogen | Human acute lymphoblastic leukemia cells |
Reported Applications | Immunohistochemistry (frozen) Immunofluorescence Flow cytometry |
Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity | >95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from cell culture supernatant in an animal-free facility |
Purification | Protein G |
RRID | AB_1107669 |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
抗人转铁蛋白受体1抗体

应用
反应种属
human

背景
研究领域
Cancer Biology, Tumor Antigens
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