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产品介绍
产品介绍
产品信息
商品描述
TGF-β RI Kinase Inhibitor VII is a cell-permeable quinoline compound which has been reported to act as a potent ATP-competitive inhibitor of ALK5/TGF-β Receptor I kinase activity, while inhibiting c-Src only at higher concentrations. It has been additionally reported to block Smad2/3 transcription activity and TGF-β-induced Smad2 phosphorylation in human lung cancer epithelial cell line A549.
分子量
351.4
可溶性
DMSO and ethanol
外观
off-white Solid
应用
实验应用
An inhibitor of ALK5/TGF-β Receptor I kinase activity
背景
分子式
C21H21NO4
CAS号
666729-57-3
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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