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产品介绍
产品介绍
产品信息
纯化方式
>98% (HPLC)
抗原名称
KV1.2 K+ channels
序列号
VFINAKCRGSPECLPKCKECIGKAAGKCMNGKCKCYP.
商品描述
Tityustoxin-Kα-ATTO Fluor-594 (#STT-360-AR) is a highly pure, synthetic, and biologically active conjugated peptide toxin.
分子量
~4900 Da
生物活性
Tityustoxin-Kα blocks cloned KV1.2 with high potency1,2.Using Alomone labs Tityustoxin-Kα-ATTO Fluor-594 in microscopy technique, Williams R.W. et al. showed recently that stimulating adenylate cyclase (AC) decreased surface KV1.2 within the pinceaus of cerebellar basket cell (BC) axon terminals3.
可溶性
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min). Avoid exposure to light. The product is lyophilized in 0.5 ml conical vial.
浓度
0.5-50 nM.
形式
Lyophilized
背景
翻译后修饰
Disulfide bonds between Cys7-Cys28, Cys13-Cys33 and Cys17-Cys35. Amino acid Alanine at position 20 was replaced by Cysteine (Bold in the sequence).
制备和贮存
存储溶液
Up to two weeks at 4°C or three months at -20°C. Avoid exposure to light.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. Avoid exposure to light.
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