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Tizoxanide
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产品介绍
产品介绍
产品信息
商品描述
Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus.
分子量
265.3
纯度
>98%
可溶性
DMSO : ≥ 38 mg/mL
外观
淡黄色粉末
In vitro(体外研究)
<p>Tizoxanide (TIZ) induces mild mitochondrial uncoupling and activate <a href="/Targets/AMPK.html" target="_blank" style="color: #6a4b92; font-weight:bold;">AMPK</a> in hepatocytes<sup><a href="javascript:goCoordinate('cpd_References1');"></a></sup>.<br/> Tizoxanide (TIZ) inhibits hepatitis C virus (<a href="/Targets/HCV.html" target="_blank" style="color: #6a4b92; font-weight:bold;">HCV</a>) replication in <a href="/Targets/HCV.html" target="_blank" style="color: #6a4b92; font-weight:bold;">HCV</a> replicon systems<sup><a href="javascript:goCoordinate('cpd_References1');"></a></sup>.</p>
In vivo(体内研究)
<p>Tizoxanide (TIZ) (10 mg/kg; i.v.) can pass the BBB and distribute to the brain tissue. Tizoxanide retains in brain is obviously longer than that in plasma<sup><a href="javascript:goCoordinate('cpd_References1');"></a></sup>.</p>
背景
别名
替唑尼特；TIZ
分子式
C10H7N3O4S
CAS号
173903-47-4
制备和贮存
保存方式
Store at -20℃ for one year (Powder); Store at 2-4℃ for two weeks; Store at -20℃ for six months after dissolution.
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