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品牌: BD Pharmingen
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对比
咨询反应种属:
Human (QC Testing), Rhesus, Cynomolgus, Baboon (Tested in Development)
来源宿主:
Mouse IgG1, κ
产品介绍
产品使用步骤推荐 产品介绍
产品信息
荧光素标记
抗原名称
TNF

宿主
Mouse IgG1, κ

免疫原
Recombinant Human TNF

简单描述
The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF-α) protein. TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN-γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.

商品描述
MAb11
The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF-α) protein. TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN-γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.

同种型
Mouse IgG1, κ

克隆号
克隆 MAb11 (RUO)

浓度
0.2 mg/ml

产品详情
Alexa Fluor™ 700
Alexa Fluor™ 700 dye is part of the BD red family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 697 nm and an emission maximum (Em Max) at 719-nm. Alexa Fluor™ 700 is designed to be excited by the Red (627–640-nm) laser and detected using an optical filter centered near 720-nm (e.g., a 720/40-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
Alexa Fluor™ 700
697 nm
719 nm
BD化合物表
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应用
实验应用
Intracellular staining (flow cytometry) (Routinely Tested)

反应种属
Human (QC Testing), Rhesus, Cynomolgus, Baboon (Tested in Development)

目标/特异性
TNF

背景
别名
Tumor necrosis factor alpha; TNF-a; TNF-α; TNFSF2; Cachectin

制备和贮存
存储溶液
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

保存方式
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
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