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TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2)


品牌: MyBioSource








反应种属:
Human
Human
实验应用:
ELISA (EL/EIA), Western Blot (WB)
ELISA (EL/EIA), Western Blot (WB)
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.

抗原名称
TOB2

免疫原
Full length recombinant corresponding to aa1-344 from human TOB2 (AAH38957) with GST tag. MW of the GST tag alone is 26kD.

商品描述
TOB2 is a 344aa rich novel member of the Tob:BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG:Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0:G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues.

克隆号
2F2-1A7

形式
Supplied as a liquid in PBS, pH 7.2.

产品类型
Monoclonal

应用
实验应用
ELISA (EL/EIA), Western Blot (WB)

反应种属
Human

背景
别名
Anti -TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2)

制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
10766

UniProt ID
Q14106
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