TopBP1 (B-7)

鼠

抗-TopBP1 抗体 B-7 是小鼠单克隆 IgG1 κ，TopBP1抗体, 在10篇文献中引用，规格为200 µg/mlraised against a peptide mapping at the C-terminus of TopBP1 of human originTopBP1 抗体 (B-7) 推荐用于WB, IP, IF 和 ELISA，检测human 来源的 TopBP1抗-TopBP1 抗体 (B-7) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取TopBP1 (B-7): sc-271043的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 TopBP1 Antibody (B-7) for WB 的首选应用二抗。这些试剂现在以套装形式提供TopBP1 Antibody (B-7)。 (见下方订购信息). 查看产品引用文献(10) TopBP1 Antibody (B-7) is a high quality monoclonal TopBP1 antibody (also designated TopBP1 antibody) suitable for the detection of the TopBP1 protein of human origin. TopBP1 Antibody (B-7) is available as both the non-conjugated anti-TopBP1 antibody form, as well as multiple conjugated forms of anti-TopBP1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Human DNA topoisomerase II binding protein 1 (TopBP1) contains eight BRCT motifs that are found in proteins regulating the DNA damage response, transcription, and replication. In addition, TopBP1 shares sequence similarity with the fission yeast Rad4/Cut5 protein and the budding yeast DPB11 protein, both of which are required for DNA damage control and/or replication checkpoint control. Phosphorylation of TopBP1 occurs in response to DNA double-strand breaks and replication blocks. TopBP1 forms nuclear foci and localizes to the sites of DNA damage or the arrested replication forks. Downregulation of TopBP1 leads to reduced cell survival, probably due to increased apoptosis. TopBP1 functions as a transcriptional coactivator by e

Replacement monoclonal antibody for: sc-22858, sc-22859, sc-32923.

拓扑异构酶2结合蛋白1抗体;磷酸盐缓冲液

HumanTOPBP1