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产品介绍
产品介绍
产品信息
抗原名称
DNA Alkylator_Crosslinker
商品描述
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
分子量
189.22
纯度
＞98%
可溶性
DMSO : 91 mg/mL (480.9 mM)
外观
white solid
In vitro(体外研究)
Thio-TEPA exhibits alkylating activity in rat liver slice incubation. Thio-TEPA does not affect the viability of rat liver slices, and is not accumulated in the slices at all doses of 2, 5, 10 mM.
In vivo(体内研究)
Thio-TEPA (20 mg/kg, i.p.) with total body irradiation (TBI) enhances donor-type blood chimerism during the first 10 weeks but is not dramatically higher than that of TBI group alone. Thio-TEPA alone improves both short- and long-term engraftment in mice.
背景
别名
三亚乙基硫代磷酰胺；Thio-TEPA
分子式
C6H12N3PS
CAS号
52-24-4
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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