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产品介绍
产品信息
抗原名称
Antioxidant

商品描述
Troloxa is a vitamin E analogue, used in reducing oxidative stress or damage.

分子量
250.3

纯度
>98%

可溶性
DMSO:50 mg/mL (199.77 mM)

外观
白色至米色结晶粉末

In vitro(体外研究)
Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-Carboxylic Acid) is a vitamin E analog and a direct scavenger of peroxyl and alkoxyl radicals. Trolox impairs PT4 cell survival, has minor effects on ROS levels and causes wide deregulation of cell cycle genes. Trolox enhances As2O3-mediated apoptosis in APL, myeloma, and breast cancer cells. Trolox inhibits DNA damage formation induced by singlet oxygen in human lymphoblast WTK-1 cells and protects red blood cells during photodynamic treatment.

In vivo(体内研究)
After cerebral ischemia reperfusion, Trolox prescription increases anti-apoptotic proteins and decreased proapoptotic proteins thus protects neurons of the hippocampus and caused improvement of memory.

背景
别名
水溶性维生素E;奎诺二甲基丙烯酸

分子式
C14H18O4

CAS号
53188-07-1

制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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