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产品介绍
产品介绍
产品信息
纯化方式
Affinity purified on immobilized antigen.
宿主
Rabbit
免疫原
Peptide HKLSEKLNPSVLRC, corresponding to amino acid residues 822-835 of mouse TRPC3 (Accession Q9QZC1). Intracellular, C-terminus.
简单描述
A Rabbit Polyclonal Antibody to TRPC3 Channel Conjugated to the Fluorescent Dye ATTO-594
商品描述
Anti-TRPC3 Antibody (#ACC-016) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot, immunoprecipitation, immunohistochemistry, immunocytochemistry, and indirect flow cytometry applications. It has been designed to recognize TRPC3 from mouse, rat, and human samples.
同种型
Rabbit IgG.
纯度
Affinity purified on immobilized antigen.
形式
Lyophilized
组成成分
抗蛋白抗体
基因
TRPC3
应用
实验应用
IF, IHC
反应种属
H, M, R
背景
别名
Short transient receptor potential channel 3, Transient receptor protein 3, TRP3
背景
The Transient Receptor Potential (TRP) superfamily is one of the largest ion channel family and consists of diverse groups of proteins. In mammals about 28 genes encode the TRP ion channel subunits. The mammalian TRP superfamily comprises six subfamilies known as the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipins), TRPP (polycystin) and the TRPA (ANKTM1) ion channels.1-4
The TRPC subfamily consists of seven proteins named TRPC1 to 7 which can be further divided into four subgroups based on their sequence homology and functional similarities: TRPC1; TRPC4 and TRPC5; TRPC3, TRPC6, TRPC7 and TRPC2.2,5 They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues.
TRPC3, TRPC6 and TRPC7 form non-selective cationic channels that are activated by the stimulation of GPCRs.
TRPC3 was shown to be activated by DAG and SOC, in heterologous expression systems.6,7
The TRPC subfamily consists of seven proteins named TRPC1 to 7 which can be further divided into four subgroups based on their sequence homology and functional similarities: TRPC1; TRPC4 and TRPC5; TRPC3, TRPC6, TRPC7 and TRPC2.2,5 They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues.
TRPC3, TRPC6 and TRPC7 form non-selective cationic channels that are activated by the stimulation of GPCRs.
TRPC3 was shown to be activated by DAG and SOC, in heterologous expression systems.6,7
制备和贮存
溶解方法
50 µl double distilled water (DDW).
保存方式
The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
数据库链接
Entrez-Gene ID
22065
UniProt ID
Q9QZC1
研究资源识别码
AB_2040237.
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