
产品介绍
产品信息
宿主
mouse

简单描述
抗-ULBP1 抗体 3F1 是小鼠单克隆 IgM κ,ULBP1抗体, 在5篇文献中引用,规格为200 µg/mlraised against purified human ULBP1推荐用于 human 来源的ULBP1 IP, IF 和 FCM检测also provided azide-free for blocking, sc-53131 L, 200 µg/0.1 ml关于如何获取ULBP1 (3F1): sc-53131的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。目前,我们还没有完成ULBP1 抗体 (3F1)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(5) ULBP1 Antibody (3F1) is a high quality monoclonal ULBP1 antibody (also designated ULBP1 antibody) suitable for the detection of the ULBP1 protein of human origin. ULBP1 Antibody (3F1) is available as the non-conjugated anti-ULBP1 antibody. The immune system contains genetically encoded subsystems, which monitor the extracellular environment in order to eliminate pathogens and resolve abnormal or transformed tissues. Cytomegalovirus UL16 binding proteins, known as ULBPs, are GPI-linked glycoproteins that belong to the extended MHC class I family and are distantly related to MHC class I polypeptide-related sequence B, known as MICB. ULBP and MICB proteins are ligands for the activating receptor NKG2D/DAP10, which causes lymphocyte activation resulting in the secretion of cytokines, such as interferon-gamma, and tumor cell lysis (2-4). The interaction of ULBP or MICB with NKG2D/DAP10 can be blocked by the soluble form of UL16. ULBPs stimulate cytokine and chemokine production from NK cells, CD8 alpha/beta T cells, and gamma/delta T cells. Soluble forms of ULBPs induce protein tyrosine phosphorylation and activation of the Janus kinase 2, STAT5, extracellular signal-regulated kinase, mitogen-activated protein kinase and phosphatidylinositol 3-kinase (PI 3-kinase)/Akt signal transduction pathways.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-20567, sc-20568, sc-33564.

组成成分
IGM-免疫球蛋白M型抗体

应用
实验应用
IP, IF, FCM

数据库链接
Entrez-Gene ID
80329

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