URB 597 (10 mg)

1383884

Potent and selective FAAH inhibitor

338.4

Cyclohexylcarbamic acid 3'-(Aminocarbonyl)-[1,1'-biphenyl]-3-yl ester

Potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC₅₀ values are 3 and 5 nM in human liver and rat brain, respectively). Exhibits no significant inhibitory activity against a variety of receptors, ion channels and enzymes, including human cannabinoid receptors and rat monoacylglycerol lipase. Displays antiallodynic and antihyperalgesic activity in an inflammatory pain model.

≥99% (HPLC)

Soluble to 50 mM in DMSO

NC(C1=CC(C2=CC=CC(OC(NC3CCCCC3)=O)=C2)=CC=C1)=O

C₂₀H₂₂N₂O₃

546141-08-6