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产品介绍
产品介绍
产品信息
简单描述
Vimentin (G146R) (139-159)-biotin peptide is a biotinylated version of a mutant isoform of the cytoskeleton intermediate filament protein vimentin, vimentinG146R, which undergoes citrullination and has been found as the citrullinated form in the synovial fluid of rheumatoid arthritis patients.1 Vimentin is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) under high calcium concentrations, which can occur during macrophage apoptosis.2,3 Cayman’s Vimentin (G146R) (139-159)-biotin Peptide is intended for use as a negative control in the detection of autoantibodies against citrullinated vimentinG146R and is the non-citrullinated form of Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide (Item No. 37625).WARNING This product is not for human or veterinary use.
商品描述
A biotinylated mutant vimentin peptide
分子量
2,876.25
产品类型
Biochemicals/Peptides,Labeling & Detection
背景
别名
Synonyms:Biotin-GQGKSRLRDLYEEEMRELRRQ VIM (G146R) (139-159)-biotin
研究领域
Cancer,Cell Biology/Cell Death/Apoptosis/Cytoskeleton & Motor Proteins,Epigenetics, Transcription, & Translation/Writers/Citrullination,Immunology & Inflammation/Autoimmunity/Rheumatoid Arthritis/Innate Immunity/Pulmonary Diseases
制备和贮存
保存
≥ 3 years
保存方式
-2°C
数据库链接
UniProt ID
P867
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