ATP6V0A2 (HRP)

Recombinant protein corresponding to aa476-549 from human V-type proton ATPase 116kD subunit a isoform 2 protein.

Suitable for use in ELISA. Other applications not tested.

Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in ELISA. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human ATP6V0A2.

V-type proton ATPase 116kD subunit a isoform 2 (V-ATPase 116kD isoform a2) (Lysosomal H(+)-transporting ATPase V0 subunit a2) (TJ6) (Vacuolar proton translocating ATPase 116kD subunit a isoform 2), ATP6V0A2

Q9Y487