VRK1 (A-11)

mouse

抗-VRK1 抗体 A-11 是小鼠单克隆 IgG1 κ，VRK1抗体, 在2篇文献中引用，规格为200 µg/mlraised against a peptide mapping within an internal region of VRK1 of human originVRK1 抗体 (A-11) 推荐用于WB, IP, IF, IHC(P) 和 ELISA，检测human 来源的 VRK1; 也和以下物种反应，包括： bovine抗-VRK1 抗体 (A-11) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取VRK1 (A-11): sc-271061的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 VRK1 Antibody (A-11) for WB and IHC(P) 的首选应用二抗。这些试剂现在以套装形式提供VRK1 Antibody (A-11)。 (见下方订购信息). 查看产品引用文献(2) VRK1 Antibody (A-11) is a high quality monoclonal VRK1 antibody (also designated VRK1 antibody) suitable for the detection of the VRK1 protein of mouse, rat and human origin. VRK1 Antibody (A-11) is available as both the non-conjugated anti-VRK1 antibody form, as well as multiple conjugated forms of anti-VRK1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Human vaccina-related kinases 1 and 2 (VRK1,2) are NLS-containing, serine/threonine poxvirus-related kinases that are similar to casein kinase-1 family members. These VRK kinases phosphorylate transcription factors related to stress responses, such as p53. As an upstream regulator of p53, VRK-1 is capable of phosphorylating phosvitin, casein, histone 2b and myelin basic protein. VRK1 co-localizes with ATF2 in the nucleus and can form a stable complex. VRK1 phosphorylates ATF2 mainly on Thr 73, stabilizing the ATF2 protein and increasing its intracellular level. VRK1 phosphorylates human p53 in Thr18 and disrupts p53-Mdm2 interaction in vitro. VRK1 phosphorylates c-Jun in Ser 63 and Ser 73 in

Replacement monoclonal antibody for: sc-15238, sc-15239.

牛痘相关激酶1抗体

HumanVRK1

m, r, h

7443