VWF (C-12)

VWF (C-12)

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品牌: SantaCruz
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反应种属:
m, r, h
来源宿主:
mouse
产品介绍
产品信息
宿主
mouse
简单描述
von Willebrand Factor/VWF抗体(C-12)是小鼠单克隆IgG1 κ, 在39篇文献中引用,规格为200 µg/ml特异性抗原位于human物种的VWF的C-terminus附近的氨基酸2779-2813之间抗-von Willebrand Factor/VWF 抗体 (C-12) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 VWF抗-von Willebrand Factor/VWF 抗体 (C-12) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取von Willebrand Factor/VWF (C-12): sc-365712的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP 和 m-IgGκ BP-HRP 是 von Willebrand Factor/VWF Antibody (C-12) for WB 的首选应用二抗。这些试剂现在以套装形式提供von Willebrand Factor/VWF Antibody (C-12)。 (见下方订购信息). 查看产品引用文献(37) Von Willebrand disease is a congenital bleeding disorder caused by defects in the von Willebrand factor protein (VWF). VWF is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets, and it is involved in the coagulation of blood at injury sites. VWF acts as a carrier protein for Factor VIII, a cofactor required for coagulation, and it promotes platelet adhesion and aggregation. Several factors are known to stimulate the binding of VWF to platelets, including glycoprotein 1b, ristocetin, botrocetin, collagen, sulphatides and heparin. Of the several domains contained within VWF, the A1, A2 and A3 domains have been shown to mediate this activation. VWF is thought to undergo a variety of posttranslational modifications that influence the affinity and availability for Factor VII, including cleavage of the propeptide and formation of N-terminal intersubunit disulfide bonds.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® and
克隆类别
Replacement monoclonal antibody for: sc-8068, sc-14014.
基因
HumanVWF
应用
反应种属
m, r, h
数据库链接
Entrez-Gene ID
7450;22371
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货号:
sc-365712
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询价
200μg/ml
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