WAY 100635 maleate (10 mg)

11957721

Potent 5-HT_1A antagonist; also D₄ agonist

538.64

N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate

Potent, silent antagonist of 5-HT_1A receptors (IC₅₀ = 2.2 nM; K_i = 0.84 nM for rat 5-HT_1A receptors). Displays 100-fold selectivity for 5-HT_1A over other 5-HT subtypes. Also exhibits agonist activity at dopamine D₄ receptors.

≥99% (HPLC)

Soluble to 25 mM in water

O=C(C4CCCCC4)N(C3=NC=CC=C3)CCN(CC2)CCN2C1=C(OC)C=CC=C1.O=C(\C=C/C(O)=O)O

C₂₅H₃₄N₄O₂.C₄H₄O₄

1092679-51-0