WAY 316606 hydrochloride (10 mg)

25186563

Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling

484.94

5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide hydrochloride

Secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC₅₀ = 0.65 μM); prevents sFRP-1 from interacting with Wnt and thus increases Wnt signaling. Increases total bone area in a murine calvarial organ culture assay.

≥99% (HPLC)

Soluble to 20 mM in DMSO

O=S(C1=CC=C(C(F)(F)F)C(S(NC3CCNCC3)(=O)=O)=C1)(C2=CC=CC=C2)=O.Cl

C₁₈H₁₉F₃N₂O₄S₂.HCl

1781835-02-6