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Wnt3a (C64F2) Rabbit mAb
Wnt3a (C64F2) Rabbit mAb

Wnt3a (C64F2) Rabbit mAb

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品牌： CST
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    分子量：
    42
    42
    反应种属：
    Mouse
    Mouse
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    产品介绍
    产品信息
    抗原名称
    Wnt3a
    来源纯化
    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu256 of human Wnt3a.
    宿主
    Rabbit
    简单描述
    Monoclonal Antibody for studying Wnt3a. Cited in 53 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, Wnt3a (C64F2) Rabbit Monoclonal Antibody (CST #2721) is ready to ship.
    商品描述

    Product Usage Information

    ApplicationDilution
    Western Blotting1:1000
    Immunoprecipitation1:50
    分子量
    42
    内毒素水平
    人, 大鼠
    研究领域
    癌症,发育生物学与干细胞研究,纤维化,神经科学,
    应用
    反应种属
    Mouse
    预测反应种属
    Human,Rat,
    目标/特异性

    Specificity/Sensitivity

    Wnt3a (C64F2) Rabbit mAb detects transfected Wnt3a protein in L cells and the conditioned medium from L/Wnt3a cells.

    Species Reactivity:

    Mouse

    敏感性
    Transfected Only
    背景
    背景
    The Wnt family includes several secreted glycoproteins that play important roles in animal development (1). There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins (2). Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways (3). The canonical Wnt/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family (4). Aberrant activation of Wnt signaling pathways is involved in several types of cancers (5). 1.Cadigan, K.M. and Nusse, R. (1997) Genes Dev. 11, 3286-3305. 2.Moon, R.T. et al. (1997) Trends Genet. 13, 157-162. 3.Kohn, A.D. and Moon, R.T. (2004) Cell Calcium 38, 439-446. 4.Logan, C.Y. and Nusse, R. (2004) Annu. Rev. Cell Dev. Biol. 20, 781-810. 5.Giles, R.H. et al. (2003) Biochim. Biophys. Acta. 1653, 1-24.
    研究领域
    癌症,发育生物学与干细胞研究,纤维化,神经科学,
    翻译后修饰
    Unmodified
    制备和贮存
    保存方式
    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
    数据库链接
    Entrez-Gene ID
    89780
    UniProt ID
    P56704

    参考图片

    Western blot analysis of total cell lysates and conditioned medium from L cells overexpressing mouse Wnt3a, compared with parental L cells, using Wnt3a (C64F2) Rabbit mAb.

    使用Wnt3a（C64F2）Rabbit mAb兔单抗，对过表达小鼠Wnt3a的L细胞和对照亲本的L细胞的全细胞裂解液和条件培养基进行western blot分析。

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    货号：
    2721T
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    询价
    供应商现货
    20ul
    100ul
    抗体送U盘
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    当前规格1件起购 
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    预计5-6个工作日送达，快递: 免运费，若需干冰额外收费
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