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产品介绍
产品介绍
产品信息
抗原名称
VEGFR1,Src,Abl
商品描述
ZM306416 is a vascular endothelial growth factor receptor (VEGFR) antagonist.
分子量
333.74
纯度
98%
可溶性
DMSO : 62 mg/mL (185.8 mM)
外观
类白色粉末
In vitro(体外研究)
ZM-306416 induces selective antiproliferative effect toward the EGFR-addicted NSCLC cell lines H3255 and HCC4011 with IC50 of 0.09 µM and 0.072 µM, respectively. ZM-306416 inhibits granule formation with IC50 of 0.67 μM. ZM-306416 significantly inhibits the ERRα assay with IC50 of 7.3 μM in the GeneBLAzer T-Rex RORγ-UAS-bla HEK293T cell line. ZM306416 (300 nM) completely inhibits PAA secretion and stimulates I uptake in human thyroid follicular cells. ZM306416 (300 nM) abolishes pVEGFR2 (Y1214) expression in human thyroid follicular cells. ZM306416 ( ZM306416 (1 μM) enhances follicle formation and decreased nuclear distribution in human thyroid follicular cells.
背景
别名
ZM-306416;ZM 306416;CB 676475; ZM-306416; ZM306416; CB-676475; CB676475
分子式
C16H13ClFN3O2
CAS号
690206-97-4
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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