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产品介绍
产品介绍
产品信息
抗原名称
STK19 (D89N):27.94 nM, STK19 (WT):23.96 nM
商品描述
Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).
分子量
385.5
纯度
98%
可溶性
DMSO:41 mg/mL (106.36 mM)
In vitro(体外研究)
ZT-12-037-01 significantly inhibits mutant NRAS-STK19-driven melanocyte colony formation and proliferation.
In vivo(体内研究)
ZT-12-037-01 as a specific STK19-targeted inhibitor and it effectively blocks oncogenic NRAS-driven melanocyte malignant transformation and melanoma growth in vivo.
背景
分子式
C21H31N5O2
CAS号
2328073-61-4
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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